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The Swamp Thing returns to battle the evil Dr. Arcane, who has a new science lab full of creatures transformed by genetic mutation, and chooses Heather Locklear as his new object of affection.

After her mother’s mysterious death, Abby Arcane (Heather Locklear) travels to the Florida swamps to confront her evil stepfather Dr. Arcane (Louis Jourdan), who had been resurrected with a ludicrous explanation after his death in the first film. In an attempt to stave off the effects of aging and assisted by Dr. Lana Zurrell (Sarah Douglas), Dr. Arcane combines genes from various swamp animals and human beings, creating an army of monsters. Dr. Arcane tries to use his stepdaughter Abby in his genetic experiments until she is rescued by Swamp Thing (Dick Durock), a scientist previously transformed into a bog creature after a confrontation with the evil doctor and a conscience-stricken Dr. Zurrell.

Based on the DC Comics (later Vertigo Comics) title Swamp Thing; sequel to the 1982 horror film Swamp Thing (directed by Wes Craven).

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